Chicken and Biscuit Casserole – A Comforting, Cheesy Delight

There’s nothing quite like a warm, hearty casserole fresh out of the oven, and this Chicken and Biscuit Casserole is the ultimate comfort food. With tender shredded chicken, fluffy biscuits, crispy bacon, and gooey melted cheese, every bite is packed with rich, creamy goodness. This dish brings back nostalgic memories of home-cooked meals, making it a family favorite for generations.

Perfect for busy weeknights, this easy casserole recipe requires minimal prep and is ready in under an hour. Whether you're feeding a crowd or looking for a satisfying dinner with leftovers, this recipe delivers flavor, texture, and warmth in every serving.

Ingredients (Serves 8)

Each ingredient plays a key role in achieving the perfect balance of creamy, cheesy, and savory flavors.

  • 2 cups shredded cheddar cheese, divided – Adds a rich, cheesy texture to the casserole.
  • 3 cups cooked shredded chicken – A great way to use up leftover rotisserie chicken or meal-prepped chicken.
  • 2 tablespoons ranch seasoning mix – Infuses the dish with bold, zesty flavor.
  • 2 cans (10.5 oz each) condensed cream of chicken soup – Forms the creamy base of the casserole.
  • 1/4 cup cooked and crumbled bacon – Adds a smoky, crispy bite.
  • 1 1/2 cups sour cream – Enhances the creaminess and adds a subtle tang.
  • 1 (12 oz) can refrigerated biscuits – Provides a soft, buttery texture that perfectly complements the creamy filling.

Step-by-Step Instructions

1. Preheat Your Oven

Set your oven to 350°F (175°C) to ensure even cooking. Lightly grease a 9×13-inch baking dish to prevent sticking.

2. Prepare the Creamy Mixture

In a large mixing bowl, combine:

  • 1 cup of shredded cheddar cheese
  • Shredded chicken
  • Ranch seasoning
  • Cream of chicken soup
  • Sour cream
  • Crispy bacon bits

Stir until everything is well incorporated.

3. Cut the Biscuits

Open the can of refrigerated biscuits and cut each biscuit into four equal pieces. This helps distribute them evenly throughout the casserole for a perfect balance of flavors.

4. Combine the Biscuits with the Mixture

Gently fold the biscuit pieces into the creamy chicken mixture, making sure each piece is coated. This ensures they bake up soft and flavorful.

5. Assemble in the Baking Dish

Transfer the mixture to the greased baking dish and spread it evenly. Sprinkle the remaining cup of cheddar cheese over the top for an irresistible golden, cheesy crust.

6. Bake to Perfection

Place the dish in the preheated oven and bake for 25–35 minutes, or until the biscuits are golden brown and fully cooked through.

7. Let It Rest & Serve

Remove from the oven and let it sit for 5 minutes before serving. This allows the sauce to thicken slightly and ensures every bite is rich and creamy.

Why You’ll Love This Chicken and Biscuit Casserole

  • Easy to Make – Uses simple ingredients and comes together quickly.
  • Family-Friendly – A meal everyone will love, from kids to adults.
  • Creamy & Cheesy – The perfect balance of savory chicken, gooey cheese, and soft biscuits.
  • Great for Leftovers – Tastes even better the next day.

Pro Tips for the Best Casserole

  • Use Rotisserie Chicken – It saves time and adds extra flavor.
  • Don’t Overmix the Biscuits – Gently folding them in prevents them from getting mushy.
  • Add Extra Flavor – Try mixing in sautéed onions, garlic, or a dash of hot sauce for a little kick.
  • Make it Crispy – For an extra crispy topping, broil the casserole for the last 2–3 minutes.

What to Serve with Chicken and Biscuit Casserole

Pair this dish with a light and refreshing side to balance the richness:

  • Steamed or roasted vegetables (green beans, broccoli, or carrots)
  • A crisp side salad with a tangy vinaigrette
  • Garlic butter green beans for an extra pop of flavor
  • Mashed potatoes if you want an even heartier meal

Final Thoughts

This Chicken and Biscuit Casserole is the ultimate comfort food—rich, creamy, and packed with cheesy goodness. Whether you're making it for a family dinner, potluck, or meal prep, this dish will always be a hit.

Give this recipe a try and enjoy a warm, homemade meal that’s both simple and satisfying. Happy cooking!